Putting this here because probably the most people will set it.
Due to the crisis in the computing industry over Meltdown, Spectre, and the like, operating system developers have been working diligently with academia, CPU developers and hardware manufacturers to provide solutions. Some of these solutions require both hardware changes in the form of CPU microcode and software changes in the form of operating system and other subsystem mitigations. Despite what might be reported in the press, this work is ongoing.
Probably everyone is familiar with the warning from motherboard providers: "Do not update your bios unless you are experiencing a problem." However some changes in the latest OS releases require corresponding bios updates. AMD is particularly affected because they don't typically provide "early microcode update" as part of OS start up like Intel does.
Case in point:
Everyone has to decide for themselves whether to attempt bios update, and take responsibility if something fails and you brick your motherboard. But particularly if using Virtual Machines, we highly recommend keeping your bios updated, especially for AMD platforms.