By removing it, do you mean removing after booting, when system is running/powered on? Only reason I want to run it without GPU is to save on power, won't save much, but why waste energy :). That's exactly why I got this board, at the time, it looked like the best one with enough PCIe slots. Currently have 5900X, but probably could be replaced with 5700G - then again, spending money on new CPU would cost more than savings on energy usage :).