I went and downloaded the oldest Windows 10 drivers on AMD's site since I don't use it for gaming and merely use it for a HTPC. I also have this audio issue which started about 2 months ago after working flawlessly for 2 years. I tried recreating the VM, using a different BIOS, using a different AMD card, etc. The only way I have found to get audio is to turn off the unraid server and turn it back on. Then on the initial start of the VM i have audio but if the VM has to reboot for anything I am hosed until I do a reboot on the unraid server.
I might try the removing of AMD high definition driver next time I want to waste a Sunday but I have little to no faith that will help since I reverted to 2 year old drivers and STILL got the same problem.