Problem running VMs with GPU passthrough

I'm having a problem launching creating new VMs. . I attempted to install ArcoLinux using the default Arch template. Calamares installer runs fine and the O/S installs. After shutting down the VM, removing the ISO and rebooting the VM I am getting the following message:

Starting version 248.3-2-arch

/dev/vda2: clean, 464203/3260416 files, 4273307/13029719 blocks

The cursor flashes however the VM never progresses beyond this point. If I reboot the same message appears.

The log for the VM is:

-rtc base=utc,driftfix=slew \
-global kvm-pit.lost_tick_policy=delay \
-no-hpet \
-no-shutdown \
-boot strict=on \
-device pcie-root-port,port=0x8,chassis=1,id=pci.1,bus=pcie.0,multifunction=on,addr=0x1 \
-device pcie-root-port,port=0x9,chassis=2,id=pci.2,bus=pcie.0,addr=0x1.0x1 \
-device pcie-root-port,port=0xa,chassis=3,id=pci.3,bus=pcie.0,addr=0x1.0x2 \
-device pcie-root-port,port=0xb,chassis=4,id=pci.4,bus=pcie.0,addr=0x1.0x3 \
-device pcie-root-port,port=0xc,chassis=5,id=pci.5,bus=pcie.0,addr=0x1.0x4 \
-device pcie-root-port,port=0xd,chassis=6,id=pci.6,bus=pcie.0,addr=0x1.0x5 \
-device pcie-root-port,port=0xe,chassis=7,id=pci.7,bus=pcie.0,addr=0x1.0x6 \
-device pcie-root-port,port=0xf,chassis=8,id=pci.8,bus=pcie.0,addr=0x1.0x7 \
-device pcie-root-port,port=0x10,chassis=9,id=pci.9,bus=pcie.0,multifunction=on,addr=0x2 \
-device pcie-root-port,port=0x11,chassis=10,id=pci.10,bus=pcie.0,addr=0x2.0x1 \
-device ich9-usb-ehci1,id=usb,bus=pcie.0,addr=0x7.0x7 \
-device ich9-usb-uhci1,masterbus=usb.0,firstport=0,bus=pcie.0,multifunction=on,addr=0x7 \
-device ich9-usb-uhci2,masterbus=usb.0,firstport=2,bus=pcie.0,addr=0x7.0x1 \
-device ich9-usb-uhci3,masterbus=usb.0,firstport=4,bus=pcie.0,addr=0x7.0x2 \
-device virtio-serial-pci,id=virtio-serial0,bus=pci.2,addr=0x0 \
-blockdev '{"driver":"file","filename":"/mnt/user/domains/ArcoLinux/vdisk1.img","node-name":"libvirt-1-storage","cache":{"direct":false,"no-flush":false},"auto-read-only":true,"discard":"unmap"}' \
-blockdev '{"node-name":"libvirt-1-format","read-only":false,"cache":{"direct":false,"no-flush":false},"driver":"raw","file":"libvirt-1-storage"}' \
-device virtio-blk-pci,bus=pci.3,addr=0x0,drive=libvirt-1-format,id=virtio-disk2,bootindex=1,write-cache=on \
-netdev tap,fd=33,id=hostnet0 \
-device virtio-net,netdev=hostnet0,id=net0,mac=52:54:00:5f:4f:38,bus=pci.1,addr=0x0 \
-chardev pty,id=charserial0 \
-device isa-serial,chardev=charserial0,id=serial0 \
-chardev socket,id=charchannel0,fd=34,server,nowait \
-device virtserialport,bus=virtio-serial0.0,nr=1,chardev=charchannel0,id=channel0,name=org.qemu.guest_agent.0 \
-device vfio-pci,host=0000:43:00.0,id=hostdev0,bus=pci.4,addr=0x0,romfile=/mnt/user/isos/vbios/GTX1080.rom \
-device vfio-pci,host=0000:43:00.1,id=hostdev1,bus=pci.5,addr=0x0 \
-device vfio-pci,host=0000:46:00.0,id=hostdev2,bus=pci.6,addr=0x0 \
-device vfio-pci,host=0000:47:00.0,id=hostdev3,bus=pci.7,addr=0x0 \
-device vfio-pci,host=0000:48:00.0,id=hostdev4,bus=pci.8,addr=0x0 \
-device vfio-pci,host=0000:49:00.0,id=hostdev5,bus=pci.9,addr=0x0 \
-sandbox on,obsolete=deny,elevateprivileges=deny,spawn=deny,resourcecontrol=deny \
-msg timestamp=on
2021-08-01 05:20:16.609+0000: Domain id=3 is tainted: high-privileges
2021-08-01 05:20:16.609+0000: Domain id=3 is tainted: host-cpu
char device redirected to /dev/pts/0 (label charserial0)

I've not had a problem running VMs with GPU pass through before.

I've tried an install of the same O/S but used VNC instead of passing through the GPU. After install the O/S boots fine and operates through VNC. I'm presuming its some issue with the VP pass through. Ive tried two GPUs and get the same problem. One of the GPU I have used with GPU pass through previously.

Any advice?