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Intel s2600stb daul Xeon Gold 6146 help optimising bios and vm's needed

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Heya guys and gals I recently grabbed a intel s2600stb and p4000 chassis, I've got 2 xeon 6146's and 384gb of ram 12 sticks of 32gb ddr4 2666 running in 6 channel. The first 2 slots are using cpu 0, cpu 1 has 3 4 5 6. The board also has 4 oculink pcie x4 headers and 2 m.2 slots on cpu 0. I plan to use one oculink port for a egpu adaptor to add a 3rd gpu under the dual 750w psu's, I have a quadro p1000 in slot 1, slot 3 a rx 6600 slot 5 a pcie 4 slot nvme m.2 adaptor and slot 6 a LSI 9400-16i. 

 

What i'am after as a guide or info for bios settings for maximum performance and a more in depth idiots guide for vm's, I've read the asic VM tuning guide for multi socket motherboards on the forum but can't find much more. With bios settings I'm lost as there are so many options I don't understand what's best, aka interleaving memory 1 or 2 or disabled. I've know consumer boards inside and out and even understand most settings in the dell 5820 bios which is extremely advanced compared to the basic options in the p520 which I use as a gamer. I guess for the time being ill read up on numa but would love some help. Also setting up IPMI BCM and changing the lan ports I have dual 10gb ports and a 1gb IPMI BCM, I wish to be able to use the IPMI but it looks like its using it as my connection.

Have you read the manual?

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