I just upgraded from 6.18 to 6.2.1 and while my windows 10 VM boots, and seems fine, when I try to play a game, it doesn't launch. Also, sound does not appear to be working.

 

<domain type='kvm'>
  <name>Windows 10</name>
  <uuid>2d78105a-93c9-9428-1e35-4a04eb1b0e73</uuid>
  <description>Unraid Windows 10 VM</description>
  <metadata>
    <vmtemplate xmlns="unraid" name="Windows 10" icon="windows.png" os="windows10"/>
  </metadata>
  <memory unit='KiB'>4194304</memory>
  <currentMemory unit='KiB'>4194304</currentMemory>
  <memoryBacking>
    <nosharepages/>
    <locked/>
  </memoryBacking>
  <vcpu placement='static'>2</vcpu>
  <cputune>
    <vcpupin vcpu='0' cpuset='0'/>
    <vcpupin vcpu='1' cpuset='1'/>
  </cputune>
  <os>
    <type arch='x86_64' machine='pc-i440fx-2.3'>hvm</type>
  </os>
  <features>
    <acpi/>
    <apic/>
  </features>
  <cpu mode='host-passthrough'>
    <topology sockets='1' cores='1' threads='2'/>
  </cpu>
  <clock offset='localtime'>
    <timer name='rtc' tickpolicy='catchup'/>
    <timer name='pit' tickpolicy='delay'/>
    <timer name='hpet' present='no'/>
  </clock>
  <on_poweroff>destroy</on_poweroff>
  <on_reboot>restart</on_reboot>
  <on_crash>restart</on_crash>
  <devices>
    <emulator>/usr/local/sbin/qemu</emulator>
    <disk type='file' device='disk'>
      <driver name='qemu' type='raw' cache='writeback'/>
      <source file='/mnt/windowsVM/Windows 10/vdisk1.img'/>
      <target dev='hdc' bus='virtio'/>
      <boot order='1'/>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x04' function='0x0'/>
    </disk>
    <disk type='file' device='cdrom'>
      <driver name='qemu' type='raw'/>
      <source file='mnt/windowsVM/ISO/Win10_1511_English_x64.iso'/>
      <target dev='hda' bus='ide'/>
      <readonly/>
      <boot order='2'/>
      <address type='drive' controller='0' bus='0' target='0' unit='0'/>
    </disk>
    <disk type='file' device='cdrom'>
      <driver name='qemu' type='raw'/>
      <source file='mnt/windowsVM/Drivers/virtio-win-0.1.112.iso'/>
      <target dev='hdb' bus='ide'/>
      <readonly/>
      <address type='drive' controller='0' bus='0' target='0' unit='1'/>
    </disk>
    <controller type='usb' index='0' model='ich9-ehci1'>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x07' function='0x7'/>
    </controller>
    <controller type='usb' index='0' model='ich9-uhci1'>
      <master startport='0'/>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x07' function='0x0' multifunction='on'/>
    </controller>
    <controller type='usb' index='0' model='ich9-uhci2'>
      <master startport='2'/>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x07' function='0x1'/>
    </controller>
    <controller type='usb' index='0' model='ich9-uhci3'>
      <master startport='4'/>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x07' function='0x2'/>
    </controller>
    <controller type='pci' index='0' model='pci-root'/>
    <controller type='ide' index='0'>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x01' function='0x1'/>
    </controller>
    <controller type='virtio-serial' index='0'>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x03' function='0x0'/>
    </controller>
    <interface type='bridge'>
      <mac address='52:54:00:83:43:84'/>
      <source bridge='br0'/>
      <model type='virtio'/>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x02' function='0x0'/>
    </interface>
    <serial type='pty'>
      <target port='0'/>
    </serial>
    <console type='pty'>
      <target type='serial' port='0'/>
    </console>
    <channel type='unix'>
      <source mode='connect'/>
      <target type='virtio' name='org.qemu.guest_agent.0'/>
      <address type='virtio-serial' controller='0' bus='0' port='1'/>
    </channel>
    <hostdev mode='subsystem' type='pci' managed='yes' xvga='yes'>
      <driver name='vfio'/>
      <source>
        <address domain='0x0000' bus='0x01' slot='0x00' function='0x0'/>
      </source>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x05' function='0x0'/>
    </hostdev>
    <hostdev mode='subsystem' type='pci' managed='yes'>
      <driver name='vfio'/>
      <source>
        <address domain='0x0000' bus='0x00' slot='0x1b' function='0x0'/>
      </source>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x06' function='0x0'/>
    </hostdev>
    <hostdev mode='subsystem' type='usb' managed='no'>
      <source>
        <vendor id='0x17ef'/>
        <product id='0x6019'/>
      </source>
    </hostdev>
    <hostdev mode='subsystem' type='usb' managed='no'>
      <source>
        <vendor id='0x413c'/>
        <product id='0x2105'/>
      </source>
    </hostdev>
    <memballoon model='virtio'>
      <address type='pci' domain='0x0000' bus='0x00' slot='0x08' function='0x0'/>
    </memballoon>
  </devices>
</domain>

Anyone?

When I upgraded I'm fairly sure all the device numbers changed so I had to redo some of my pass-through stuff.