My syslinux boot has:
isolcpus=32-63
Originally I discovered that when I run btrfs scrub (Main -> diskx -> scrub), it doesn't respect the isolcpus i.e. it uses the cores that are supposed to be isolated (see attached screenshot).
After a few tries, I also found other activities e.g. copying files between disks (simple cp command on console) also does not respect isolcpus.
This looks to be system independent as I can reproduce this even on Unraid as a VM.
Minor