[kernel: Disabling IRQ #16]

Thrak, after doing the MSI fix were you able to install your card again with success? No being able to pass through this USB3 card would be a sort of deal breaker; my workstation has to have hot pluggable USB ports.

 

Yes, it just showed up as a working sound card in my system after rebooting.  I am short an HDMI monitor so need to solve that but that is more a $ issue than unraid/W10 (har har).  Ironically I am still on my first W10 VM and in my registry already had it all the bits there, just needed to update the field from 0 to 1 and reboot.  I am planning to do a net-new VM since I have hacked more registry settings in the last 3 days then I have done in the last 3 years trying to get W10 to behave (between sounds, network neighborhood which is still not working, and it still consuming 80% of my memory)

 

Not suggesting the MSI fix is the answer, but I do know it stopped some of my conflicts so at a minimum it was cleaner.

[kernel: Disabling IRQ #16]

I am new to unraid, and spent my entire weekend building my new toy and also ran into the IRQ16 issue.  It was related to my attempt to use a PCIe sound card vs passing sound via the GTX 970.  I removed the card and did the MSI fix and the issue went away.  So I am guessing you may have a similar issue and my guess would be the USB controller is doing it.  So my first question/suggestion would be making sure your sound via the video card is sorted out because I was getting similar issues.