I did the upgrade, it was fairly simple. I took the following steps, and it wasn't too bad. After swapping the video card, I did have a bit of trouble getting my machine to boot from the USB drive initially, but that was another issue.
1. I backed up my VM image file, vm XML setting file, and my Unraid USB stick to be safe
2. Removed Nvidia drivers from the VM
3. Shutdown VM
4. Shut down Server and swap out video card
5. Edit VM setup to pass through RTX 3060 Ti and its corresponding sound card
6. Reinstall Nvidia drivers on VM
When you boot into the VM for the first time, you will probably be stuck at a low resolution and get error 43 in device manager (assuming your VM is Windows) until you do step 6 and reinstall your video drivers from Nvidia.
That is all it was for me. Everything went well and all is working as expected.
