Well seems I finally manged to stabilize the system by changing following settings using Tips and Tweaks addon:
Disable NIC Flow Control? Yes
Disable NIC Offload?Yes
Normal CPU Scaling Governor: Performance
Previously I had NIC related settings at default and Normal CPU Scaling Governor set to on demand but now with those settings system becomes unresponsive randomly. Not sure which of the 3 settings is actually causing the issue as disabling C states in bios and just disabling NIC related settings or setting docker lan network type to ipvlan don't seem to fix the problem. Also odd system ran for long time with those settings without issues and with latest build of Unraid it becomes unstable.
At lest system seems to be functional again without needing new hardware.
