I have a Gigabyte Gaming 3. Though now I wish I had something a bit better (issues with some PCI Express lanes and disabling of slots). Running 48GB of ram, most of that goes to the OS X machine for development.
I just moved from an old i5 to my 7820x on a gigabyte gaming 3 299 board.
I run light transcoding with Plex along with a bunch of other docker processes. I also run a Win 10 VM on 3 cores with a 1080ti passthrough and a OSX High Sierra VM with a 970 passthrough.
I have 6 spinning, 1 nvme, and 1 SSD for storage.
Overall very happy with with the move from my old box. No big issues as of yet.