I had some issues with this on my FX-9590.
I kept thinking it HAD to be something to do with the CPU, reassigned different cores ect. Popping only seemed to occur when I had at least one VM using 4 cores (so it HAD to be CPU right?).
Turns out that I updated the sound card drivers for my Creative Sound Blaster X-Fi Titanium Fata1ty and now popping is non-existent!
Something to keep in mind if someone else is pulling their hair out, try updating drivers!