I can 100% confirm I never had any database corruption while my appdata was on a cache drive (and running the latest stable Unraid 6.7.x). During this time, I was running both Plex and Sonarr concurrently. I had upgraded my array 2 months ago to use just NVMe drives without a cache and after the upgrade I was only using Plex and not Sonarr. Granted I had Sonarr running, but it was not doing anything since I did not have my indexers setup. Everything was working perfectly with my appdata on /mnt/disk1. Now a few days ago, I decided to get Sonarr back up and running. Within an hour (while performing tasks in both Sonarr and Plex), I had database corruption on both my Plex and Sonarr databases. Everytime i restored a backup, it would inevitably become corrupted again. Since then, I had to disable Sonarr to prevent whatever is causing SQLite to misbehave. I have not tried any of the latest RC releases but I'll give it a shot this weekend.