ALLSTAR1JAC2899

Hey all, I am going to be building a critical 24/7 unRAID Server for the following: Critical file storage; Computer Backups; Plex; Media Finder/Downloader/Metadata/Organize (Sonarr, Radarr, Linarr, uTorrent, Sabnzbd, Plexply etc..) VMs; Home Assistant; Ubuntu; Debian; Pi-hole; Dockers; Nextcloud; File cloud and email server; Grafana; Portainer; Zabbix; OpenVPN; NetData; and a few others. What would you guys suggest for a CPU and motherboard? I am looking to spend about a thousand USD on just the CPU and MoBo, not the entire build. Just for the record, I have a Quadro P2200 and plan to use it. I will need PCiE slots available for a GPU, 10 Gig NIC, HBA, and SAS expander. And again, this is mission-critical and will run 24/7. Thanks.