u333raid

The DS380 specifications indicates it will work with DTX boards. The E3C224D4I-14S is well within the 9.6" max width spec for DTX (it's 8.4" wide). In addition, it looks like the mini-SAS connectors are just ahead of the 2 SATA connectors ... NOT on the extended portion of the board. Why don't you think this board would work ?? I was able to make a ASRock E3C224D4I-14S work in the DS380 case with some new motherboard standoffs mods. https://www.reddit.com/r/buildapc/comments/3minso/build_complete_smallest_12x_drive_diy_nas/

I got the E3C224D4I-14S to fit inside the DS380, by drilling new motherboard stand offs. http://i.imgur.com/Jl1JzDb.jpg See my build log here.