Yes, I just migrated my system from a SM CSE-836 chassis into an HL15 yesterday. No issues at all and I'm happy with the performance.
I'm sing 15 SG Exos 16TB sata disks in a ZFS pool. (3 vdevs, 5 disks, RaidZ1)
I sourced my own board, proc and ram.
I also used Noctua iPPC 2000 rpm 3-pin fans.
I have a friend using one of their pre-built configs and he's also happy with it. We both have ARC cards and are waiting on 6.13 for the updated kernel :-)
I hope this feedback helps!