I had another similar outage last week and this week after disabling macvlan, full lock up but no kernel panics and nothing really in the syslog. This time I was able to specifically correlate it to the APPDATA BACKUP plugin unfortunately as that doesn't log to syslog I can't pinpoint what action the backup plugin was doing, Disabling the functions of the backup has stopped all lockups so I believe it was a mix of macvlan and the backup.
I have the following settings enabled
backuptype: stop,backup,start each container
delete older than: 7days
keep at least: 3
appdata sources:
/mnt/user/appdata
/mnt/cache/appdata
destination: /mnt/user/backup
use compression: yes, normal
verify: yes
ignore errors: no
backup flash: yes
backup VM Meta: yes
Checking on the backup directory for any of the previous backups, the container data is all there but what is missing is the flashbackup and the VM meta data, so I am assuming that the system locks up when it attempts to backup the flashdrive. I'm not entirely sure why this happens, but my system has been stable since disabling this function.
leaving this information here for anyone else who might stumble across the same issue.