There are some issues, but they do not influent on virtualization and guests. In my case, I cannot achieve the advertised CPU boost speed and I needed to apply some patches on top of Linux kernel in order to make k10temp recognizing CPU and reporting its temperature. Also I have applied a PCI quirks patch, that allows to start VM with GPU passthrough. However I have contacted AMD support regarding this issue and seems they are aware of the problem and the upcoming AGESA 1.0.0.3ABB update should fix it, so this patch will be no longer required.