There was this in the VM logs that may be the reason
2021-09-13T09:26:37.013298Z qemu-system-x86_64: -chardev tty,id=charserial1,path=/dev/serial/by-id/usb-dresden_elektronik_ingenieurtechnik_GmbH_ConBee_II_xxxxxxxxxx-if00: warning: The alias 'tty' is deprecated, use 'serial' instead