I spoke too soon. about 6 days uptime and another soft lock. Only difference this time was I couldn't get the webgui to load at all. CA Appdata Backup did run yesterday whether that's relevant. I can't see removing that, so I'll be downgrading.
I'll chime in that I'm having the exact same issues. Was running 6.92 with a year of up time. Did some hardware upgrades and had almost 40 days uptime with a couple lock ups and decided to update after some troubleshooting. Updated to 6.11.1 a week ago I started getting the soft lock where I could only see the unraid banner in the webgui. I can only hard reboot and it seems to lock up after 2-3 days every time now. Keyboard is also unresponsive plugged directly into server after this happens.
Everything seems to function except Binhex-Qbittorrent from what I can tell. I've enabled Pre-allocated disk space and removed the following plug ins to see if it makes any difference.
Unassigned Devices
Unassigned Devices Plus
File Activity