Now, I don't have a cache drive so I do really know quite how things work.  I presume that you took the cache drive out of the system and did not replace it.  You probably now need to verify that the system doesn't still think that the cache drive is there.  The error message you are seeing is back in Windows and Windows usually has a 'default error' message for any condition that is not in its error table.  The message is often totally unrelated to the problem as the default message doesn't say that it has not idea what the problem is!!  It presents what appears to a a valid error.  (This confuses the hell of people when you are trying to fix something!) 

Frank I used an old laptopdrive for now as a cache drive. Now it seems to be working again. Thanks all for this help. Now to keeps things running especially with some add ons that I like. Will start with sabnzb and see how it goes from there.

Will be using the cache drive for the add ons and as download location. Anyone hints or tips about this, tried  some stuff but it never worked the way I wanted it to?