I also have the 7959x, but I have yet to experience any issues after a week. It could be related to PCI-E 5.0 like you stated in tbe previous post. I chose the MSP Pro x670-P board intentionally since it has one PCI-E 4.0 x16 for my gaming GPU, one 4.0 (x4 speed) for my P2000, one 3.0 x4 for my SATA controller, and one x1 for USB adapter. It's the perfect board so far for my server needs. I have the 5.0 nvme lane populated for passthrough and the other two 4.0 nvme for cache (raid 1). Also using 4x16gb Trident Z5 Neo 6000 with Expo enabled.
Have you tried limiting the 5.0 PCI-E lane to 4.0 in BIOS?
If you have VMs, are you passing through the onboard USB controllers or the onboard audio (crashes the VM for me and I need a server reboot)?