Thank you for the reply!
It seems that my cache drives have SMART errors and I can see that in the logs too...
I/O error, dev loop2, sector 27962672 op 0x0:(READ) flags 0x80700 phys_seg 1 prio class 2
BTRFS error (device loop2: state EA): bdev /dev/loop2 errs: wr 20, rd 1, flush 1, corrupt 1, gen 0