Never had any of that model but that would be the most likely explanation, I do have some Seagate Archive drives that make a clicking sound every few seconds or minutes.
Note: Moved from the FAQ thread, @ReidSFAQ thread isn't for asking questions, there's a FAQ feedback thread but this seams more like a general forum question.
Any LSI with a SAS2008/2308/3008/3408 chipset in IT mode, e.g., 9201-8i, 9211-8i, 9207-8i, 9300-8i, 9400-8i, etc and clones, like the Dell H200/H310 and IBM M1015, these latter ones need to be crossflashed.
Disk isn't initializing correctly:
Feb 12 16:54:34 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 300)
Feb 12 16:54:38 BargeTower kernel: ata6: limiting SATA link speed to 1.5 Gbps
Feb 12 16:54:39 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 310)
Feb 12 16:54:42 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 300)
Feb 12 16:55:03 BargeTower kernel: ata6: limiting SATA link speed to 1.5 Gbps
Feb 12 16:55:04 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 310)
Feb 12 16:55:07 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 300)
Feb 12 16:55:07 BargeTower kernel: ata6: limiting SATA link speed to 1.5 Gbps
Feb 12 16:55:09 BargeTower kernel: ata6: SATA link down (SStatus 0 SControl 310)
Try swapping SATA cable with another one, just on the disk, so it also uses a different SATA port, if still the same disk is likely dead.
That is weird, but I can almost guarantee that if you connect the 4TB disk tot eh onboard controller it will work correctly, no idea why the 6TB is working, it shouldn't.
That's because you're replacing a disk, not adding one, current diags start with that disk already disable so can't see what happened but I would guess the smaller disk was not removed correctly.
Disk is showing as 2.2TB because it's on a controller that doesn't support larger disks, also likely why it's failing to format, though it shouldn't, but same happened recently to another user.
I don't see how any of these will work because the disk isn't initializing correctly, very unlikely you can mount it with any OS, yes at some point it appeared under UD, but if you check no partition was detected, so not possible to mount.
The VirtIO driver should be in every virtio ISO, I remember a user recently that was having a similar issue and the problem was the Windows ISO, you can try redownloading it from MS website.
Was it performing better with an older Unraid release, i.e., did it slow down after a recent upgrade? If yes see if downgrading to the older release brings it back to normal speed.
Connect one of the USB drives to a SATA port, if the error is the one above stop the array, unassign that disk, start array, if the emulated disk mounts correctly you can rebuild on top, just stop the array again, re-assign the disk and start array to begin rebuild, then repeat for the other disks.