The New Config option is covered Here in the online documentation accessible via the ‘Manual’ link at the bottom of the GUI or the DOCS link at the top of each forum page. The Unraid OS->Manual section in particular covers most features of the current Unraid release.
i recommend you use the option to keep all current assignment, and then just remove the drive you longer want in the array on the Main tab before starting the array to commit the change. No need to physically disconnect that drive. Your dockers, etc will stay installed.