That's a RAID controller, didn't notice in the OP, it's not recommended for Unraid, you want a HBA in IT mode, that one can still work if you create a raid0/jbod for each disk in the controller BIOS, but again, not recommended.
That's strange, make sure you grab the diags if it happens again.
Same HBA is performing normally for me, if there's an issue I would suspect some kernel/Samba change first, do you have devices connect to other controllers you could test?
Syslog rotated and is spammed with same error over and over, can't see the start of the problem, please reboot and post new diags once these start:
Oct 5 20:55:45 ****** emhttpd: error: share_luks_status, 6411: Operation not supported (95): getxattr: /mnt/user/appdata
That's a JMB585, it uses the standard AHCI driver, I have multiple of those controllers working with beta30:
[197b:0585] 04:00.0 SATA controller: JMicron Technology Corp. Device 0585
[14:0:0:0] disk ATA TOSHIBA HDWD260 0A /dev/sdp 6.00TB
[15:0:0:0] disk ATA TOSHIBA HDWD260 0A /dev/sds 6.00TB
[16:0:0:0] disk ATA TOSHIBA HDWD260 0A /dev/sdv 6.00TB
[17:0:0:0] disk ATA TOSHIBA HDWD260 0A /dev/sdy 6.00TB
[18:0:0:0] disk ATA TOSHIBA HDWD260 0A /dev/sdz 6.00TB
Full diags might give more clues.
Looks like a hardware problem, possibly there's some issue with the NVMe device or it's a compatibility issue, if you can try a different NVMe device or try that device in another computer/OS.
Can confirm this bug, if disk shares are set to auto pool shares are still exported, never noticed before since I always have disk shares enable.
For now you can go to Settings -> Global Share Settings and set "Enable disk shares" to "No"