Why are your appdata, domains, and system shares set to cache-yes? They should be prefer. After you get them moved to cache then cache-only would be even better.
This isn't the likely cause of your issues though. Just a likely cause of decreased performance due to having these on the array impacted by parity writes, and also causing array disks to spin since these are always in use.
Did you try deleting the appdata for these dockers? Of course that would be starting them from scratch.