At the moment SSDs in the main Unraid style array cannot be trimmed, but they can in a ZFS pool which is what I think you are thinking of using. You mentioned flash dries, though, did you mean that or SSD. Also, how are these dries connected? USB is subject to temporary drive disconnects which can cause problems in parity protected arrays.
The current release of Unraid DOES have a requirement of at least one drive in the main Unraid style array but if you do not intend to store anything on it then you can simply use a small USB flash drive to satisfy this requirement. It is expected a future Unraid release will remove this restriction.