Let me expand a little on this, nothing I've seen so far suggest an Unraid/btrfs problem, btrfs corruption with Unraid users is not that uncommon, though most times it's caused by hardware issues, I'm a subscriber to the btrfs mailing list and AFAIK there are no unexplained corruption issues with recent kernels, also no one else using Unraid with rc4 has complained so far, and many users have btrfs pool(s).
Data corruption detected still makes me think this was hardware related, but it's not certain, re-format the pool and see if it happens again quickly, if it does you should go back to the last known Unraid release that was stable for you and confirm it doesn't still happen.