One more update, @RikStigteris helping me confirm if like suspected having IOMMU enable on these servers is the source of the problem, preliminary results look positive since the usual errors logged on them after updating to v6.10 are gone with VT-d disable, he will now use the server normally for a few days so we can confirm if it remains all good.
Issue is possibly caused by the onboard NICs when VT-d is enable, can't tell you if it's a HP problem or some Linux issue with the new kernel, certainly nothing suggests an Unraid problem, but hopefully disabling VT-d for now fixes this, again servers with a Pentium or i3 CPU shouldn't have this issue since they don't support VT-d, though I would still recommend disabling it in the BIOS, since apparently it's enable by default, so if later they are upgraded to a Xeon and this issue still exists there won't be a problem.