I do see some nginx issues, but those are outside my wheelhouse:
2021-04-27T11:21:19.000Z,"unraid nginx: 2021/04/27 11:21:19 [error] 11092#11092: *4947 upstream timed out (110: Connection timed out) while reading response header from upstream, client: 192.168.0.13, server: , request: ""POST /webGui/include/Boot.php HTTP/1.1"", upstream: ""fastcgi://unix:/var/run/php5-fpm.sock"", host: ""unraid:7000"", referrer: ""http://unraid:7000/Dashboard"""
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: *4809 open socket #25 left in connection 10
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: *5276 open socket #19 left in connection 9
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: *5280 open socket #31 left in connection 13
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: *3413 open socket #24 left in connection 8
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: *3407 open socket #26 left in connection 18
2021-04-27T11:21:19.000Z,unraid nginx: 2021/04/27 11:21:19 [alert] 11092#11092: aborting
Make sure you only have one browser windows open in the GUI, hopefully somebody else has more ideas.