If your existing single cache drive is BTRFS, then it's probably going to be ok.
However... you do have regular backups of your appdata and any cache:only/prefer shares, right? If your server isn't rock solid, I'd strongly recommend staying with a single drive. It seems like there are many more issues reported with BTRFS cache pools than there are with single XFS cache drives.
Also, what size are the existing drives, and what size are you planning on adding?